Autophagy is the natural destructive mechanism that allows the orderly degradation and recycling of cellular components. Increased autophagy delays ageing and extends longevity.
MelaTrepein™ is a cosmeceutical active ingredient to provide a dual targeting solution to prevent or reduce skin pigmentation by activating autophagy to break down melanosomes in keratinocytes and by inhibiting melanosome uptake into keratinocytes at the same time for blemish-banned, smooth and healthy skin.
Autophagy is the natural destructive mechanism that allows the orderly degradation and recycling of cellular components. Increased autophagy delays ageing and extends longevity.
Aquatide, the first known peptide-derived SIRT1 activator, activates SIRT1 by direct interaction. SIRT1 has been known as “longevity protein” that increases lifespan of various organisms.
Aquatide also rebuild skin-barrier through Ceramide Biosynthesis. Increase of Ceramide strengthens barrier function.
Attenuates and prevents expression lines and signs caused by skin micro-contractions. Its mechanism of action is botulinum-like. Argireline induces the production of new collagen, which strengthens and redensifies the tissues.
Acquatide is an innovative biomimetic peptide which is developed from the idea of 3 specific natural sources: Lysine from Silk, Resveratrol from Fruit and PCA from skin.
Acquatide shows the following benefits:
・Improve skin moisturizing & barrier recovery
・Induce autophagy flux activity
・Increase anti-stress related genes expression
・Regenerate DEJ, and NMF, Ceramides
・Moderate irritation induced by PM2.5 & Pollen
・Reduce Acetic symptom with lower salicylic acid
・Protect dermal density and improve skin firmness
Grazie ad una combinazione sinergica di silicati e peptidi, per un effetto lifting immediato.
Diminuisce immediatamente la presenza delle rughe e delle linee di espressione, riducendo i 3 segni dell’invecchiamento degli occhi: gonfiore, occhiaie e rughe.
This peptide is composed of Acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2 and has a similar function as Botox.
Botox (botulinum neurotoxin A) is a type of toxicity released from Clostridium botulinum. Botox inhibits production of acetylcholine and has a paralyzed effect on muscles. Botox as a protease decomposes SNAP-25 and disrupts the nerve transmission and this results in muscle paralyzation. Use of Botox is considered as a common practice for wrinkle improvement.
On the other hand, PepG Aceth 5’s amino acid sequence is based on VAMP, Snap-25, syntaxin and imitates the protein SNAP-25. PepG Aceth 5 competes and deters the formation of SNARE complex. This kind of process inhibits release of neurotransmitter. From this sort of replacement approach rather than elimination we can know that PepG Aceth 5 is not toxic and it is applicable for various kinds of skin products.
Grazie all’inibizione su più livelli del meccanismo di pigmentazione cutaneo ed ad una spiccata permeabilità, Genowhite riduce in breve tempo macchie cutanee e fornisce una pelle più chiara e luminosa.
Ingredient also available in WATER-SOLUBLE version.
Defensyl™ CC-MB plays the roles of messengers to signal dermis to synthesize the materials necessary for the skin, mimics the activity of DHEA and restores cytokine balance to mature skin. It reduces the harmful effects of chronic UV radiation on the tissue and avoids inflammation. This product can be used for strengthening skin barrier and protecting against oxidation in oil systems such as lip products and make-up.
Defensyl™MB
Ingredient also available in WATER-SOLUBLE version.
Tricoll™CC-MB sequence is a normal constituent of human plasma and is generated during proteolytic degradation of proteins of the extracellular matrix after tissue injury. It is used to stimulate stem cell proliferation which boosts fibroblast and the extracellular network of collagen, elastin, glycoproteins and proteoglycans to improve overall elasticity and tension of the skin. It can be used in oil systems.
Ingredient also available in WATER-SOLUBLE version.
From the idea of “eco-beauty” born Active Box, an innovative and unique reality, in the cosmetic field, able to anticipate the marketing trends offering a wide range of exclusive active ingredients.
Our philosophy and our success is fuelled by a constant research and selection, all over the world, of new and advanced technologies and sophisticated ingredients for Personal Care applications.
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